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  • 3 granted post-doc positions in Cancer Research are now opened

    Posted: 
    Tuesday, 1 September 2015
    Expires: 
    Thursday, 15 October 2015

    3 Granted Postdoc Positions in Cancer Research are available in the lab of Prof. Pierre Sonveaux at the University of Louvain (UCL) Medical School in Brussels, Belgium. The lab has strong expertise in translational Cancer Research (http://www.uclouvain.be/420397.html).

    Postdoc 1:  A grant for a 1-year postdoc position to conduct a project in the field of cancer metabolism and autophagy. The Postdoc will perform a study aimed at developing new anticancer approaches, involving molecular biology, cellular biology and in vivo studies. Experience in molecular biology, biochemistry, cell biology as well as fluency in English are required. At least one publication in international journals with impact factor ≥ 2 is mandatory. To apply, refer to POSTDOC1.

    Postocs 2 and 3: Two grants for 1-year postdoc positions to conduct preclinical research in mice, in order to validate a new anticancer treatment and its biomarkers in collaboration with Clinics and Industry. Experience in the care and use of murine mouse models of cancer is mandatory (monitoring tumor growth and metastasis, administering treatments by gavage, ip, iv). Experience in immunohistochemistry, biochemistry, cell biology as well as fluency in English are required. At least one publication in international journals with impact factor ≥ 2 is mandatory. To apply, refer to POSTDOC2&3.

    Application deadline is October 15th, 2015. Earliest possible start date is October 1st, 2015. Applicants should submit a detailed curriculum vitae, a statement of research interests, a scan of their PhD diploma and names of at least 2 Senior Referees to pierre.sonveaux@uclouvain.be.

    Qualifications: 
    PhD in any domain of Life Sciences
    Salary: 
    good
    Employers: 
    Prof. Pierre Sonveaux, Université catholique de Louvain (UCL)
    Job type: 
    Postdoc
    Location: 
    Brussels
    Contact: 
    pierre.sonveaux@uclouvain.be
  • Postoctoral position in the metabolic phenotype of tumor cells in defined conditions of the microenvironment – in the context of 13C- magnetic resonance spectroscopy

    Posted: 
    Saturday, 30 May 2015
    Expires: 
    Monday, 22 June 2015

    Project description: The altered metabolism of tumors can be monitored with nuclear magnetic resonance (NMR) spectroscopy using NMR-active metabolites. With the implementation of hyperpolarized 13C-molecules such as 13C–pyruvate, it has become possible to measure the metabolic dynamics within a few seconds. The evaluation of the NMR-signals requires knowledge on the influence of the tumor microenvironment on the cellular uptake of metabolites, especially on how nutrient and oxygen deprivation as well as an acidic pH modulate the cellular uptake of 13C-pyruvate. For this, 3D in-vitro tumor cell structures (spheroids) maintained in various tumor-like growth conditions serve as model systems. Further biochemical investigations will focus on 1) the cellular uptake of 14C-pyruvate, 2) the activity of metabolic enzymes, and 3) the metabolic flux of 13C-pyruvate using mass spectroscopy (isotopologue profiling). This project will be done in close cooperation with the Department of Biochemistry and the Clinic for Nuclear Medicine (Klinikum rechts der Isar) at the TUM.

     

    Requirements: The candidate will have a doctoral degree (PhD), a track record of a sound theoretical and practical background in biochemistry and cell biology, preferably in oncology. Experience in working with cells and biochemical assays as required above would be a major advantage. He/she should be dedicated, creative, and diligent in performing sophisticated experiments, and have good skills in communicating concepts and results in good English, including writing publications.
    The postdoctoral position is funded for two years. 
    Please see the website (http://www.imetum.tum.de/about-the-institute/?L=1) for a description of the institute and address any further queries to otto@tum.de.
    The application, including a cover letter, full CV, a brief description of scientific achievements and interests (publications, meetings, awards, etc.), and contact information of 2-3 referees, should be sent to Dr. Angela Otto (otto@tum.de).

     

    Qualifications: 
    PhD
    Salary: 
    The salary will be according to the university tariff (TV-L).
    Employers: 
    Angela Otto
    Job type: 
    PostDoctoral position of two years
    Location: 
    Zentralinstitut für Medizintechnik, Technische Universität München
    Contact: 
    otto@tum.de Tel +49 89 289-10806 Fax +49 89 289-10805

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